Process for isolation of 10-deacetyl baccatin-III

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D30514

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active

061244821

ABSTRACT:
A novel process for isolation of 10-deacetyl baccatin-III (10-DAB) and also complete separation of paclitaxel present in the primary extract, on a commercial scale from plant extract of Taxus species by solvent crystallization without employing chromatographic separation.

REFERENCES:
patent: 5453520 (1995-09-01), Bombardelli et al.
patent: 6002024 (1999-12-01), Ramadoss et al.
*applicants U.S. application No. 9/212321.

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