Process for isolating of α-mangostin

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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11181289

ABSTRACT:
The invention relates to a process for obtaining and purifying pure α-mangostin from the rind of the fruit (mangosteen) ofGarcinia mangostana.

REFERENCES:
patent: 2002047180 (2002-02-01), None
Jefferson et al., Australian Journal of Chemistry, “Studies in the xanthone series”, 1970 , vol. 23, pp. 2539-2543.
Govindachari et al., Tetrahedron, “Xanthones ofGarcinia mangostanalinn”, 1971, vol. 27, pp. 3919-3926.
English translation of JP 2002-47180, Aug. 8, 2006.
Sakai, et al; The Structure of Garcinone E; Chem. Pharm. Bull.; vol. 45; No. 5; 1993 Pharmaceutical Society of Japan; pp. 958-960.
Chen; et al; Active Constituents Against HIV-1 Protease from Garcinia mangostana; Planta Medica; vol. 62; 1996; pp. 381-382.
Linuma, et al; Antibacterial Activity of Xanthones from Guttiferaeous Plants against Methicillin-resistant Staphylococcus aureus; J. Pharmacol.; vol. 48; 1996; pp. 861-865.
Yates, et al; the Structure of Magostin; Journal of American Chemical Society; 1958; vol. 80; pp. 1691-1700.
Gopalakrishnan, et al; Evaluation of the Antifungal Activity of Natural Xanthones from Garcinia mangostana and Their Synthetic Derivatives; J. Nat. Prod. 1997; vol. 60; pp. 519-524.

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