Process for iohexol manufacture

Details Process for iohexol manufacture Process for iohexol manufacture

1999-05-17

2000-11-28

Kumar, Shailendra

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

424 9454, C07C23305

Patent

active

061537969

ABSTRACT:
The invention provides a process for the production of iohexol comprising reacting 5-acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodophthalamide with a 2,3-dihydroxypropylating agent, the improvement comprising effecting that said process in the presence of a solvent comprising 2-methoxy-ethanol and, optionally, isopropanol.

REFERENCES:
patent: 1548594 (1925-07-01), Nordal et al.
patent: 4250113 (1981-02-01), Nordal et al.
patent: 4348377 (1982-09-01), Felder et al.
patent: 5371278 (1994-12-01), McCarthy et al.
patent: 5527926 (1996-06-01), Ranganathan et al.
patent: 5948940 (1999-09-01), Sorensen et al.
Oslo Symp. 1982: Ion Exch. Solvent Extr., PAP, V/36-V/43.

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