Process for introducing alkyl radicals into carbon chains having

Details Process for introducing alkyl radicals into carbon chains having Process for introducing alkyl radicals into carbon chains having

1981-04-03

1983-03-22

Brust, Joseph Paul

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260465R, 2604659, 260464, 560231, 560236, 562606, 564215, C07C12000, C07C12116

Patent

active

043775330

ABSTRACT:
Process for introducing a substituent selected from branched- or straight-chain alkyl radicals having from 1 to 12 carbon atoms, aralkyl or cycloalkyl radicals in which the alkyl moiety has from 1 to 4 carbon atoms, into a carbon chain bearing a stable functional group the said carbon chain having at least one proton in .alpha.-position in relation to this functional group, process whereby, in a first step, this carbon chain is reacted with a complex base comprising a mixture of alkali metal amide and alkali metal alcoholate suspended in an anhydrous organic solvent to provide temporarily a carbanion, then in a second step this carbanion is reacted in an anhydrous organic solvent with an alkyl, aralkyl or cycloalkyl halide corresponding to the substituent to be introduced.

REFERENCES:
patent: 3936490 (1976-02-01), Hofmann et al.
patent: 4127604 (1978-11-01), Chignac et al.
patent: 4155929 (1979-05-01), Chignac et al.
C.A., 2945f, (1969), vol. 70, Caubere et al.
C.A., 87770w (1971), vol. 75, Caubere et al.
C.A., 119288n (1974), vol. 81, Caubere et al.
Fieser et al., Reagents for Organic Synthesis, vol. 1, (1967), John Wiley & Sons, pp. 907, 908, 1038.

Affiliated with

Also associated with

Rating

Process for introducing alkyl radicals into carbon chains having does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for introducing alkyl radicals into carbon chains having, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for introducing alkyl radicals into carbon chains having will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1868907