Process for inhibiting undesired thiol reactions during cyanogen

Details Process for inhibiting undesired thiol reactions during cyanogen Process for inhibiting undesired thiol reactions during cyanogen

1983-08-01

1984-05-29

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, 2601127, C07G 700, C07C10352, A61K 3726

Patent

active

044513968

ABSTRACT:
The discovery of this invention is a process for inhibiting undesired irreversible thiol reactions of thiol-containing peptides while preforming desirable thiol intermediates during methionyl cleavage of said peptides using CNBr by carrying out said cleavage in the presence of thiosulfate ion.

REFERENCES:
patent: 3883500 (1975-05-01), Geiger et al.
Ho et al., Synthetic Communications 3, 317-320 (1973).
Abe et al., J. Org. Chem. 39, 253-255 (1974).
Sekita et al., Keio J. Med. 24, 203-210 (1975).

Affiliated with

Also associated with

Rating

Process for inhibiting undesired thiol reactions during cyanogen does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for inhibiting undesired thiol reactions during cyanogen, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for inhibiting undesired thiol reactions during cyanogen will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1396436