Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1987-03-20
1991-04-16
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514729, 514934, A61K 3170, A61K 31045
Patent
active
050082523
ABSTRACT:
The invention relates to a method of selectively inhibiting herpes simplex virus-specified thymidine kinase. The method comprises exposing mammalian cells infected with the virus to an effective amount of 5'-ethynylthymidine. The invention further relates to a pharmaceutical composition comprising 5'-ethynylthymidine as the active ingredient together with a pharmaceutically acceptable carrier.
REFERENCES:
Sharma et al., J. Org. Chem. 43, No. 2, pp. 367-369 (1978).
Nutter et al., the Chemical Abstracts 106:188509g (1987).
Bobek Miroslav
Cheng Yung-Chi
Health Research , Inc.
Rollins John W.
The University of North Carolina at Chapel Hill
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