Process for inhibiting blood platelet aggregation and promoting

Details Process for inhibiting blood platelet aggregation and promoting Process for inhibiting blood platelet aggregation and promoting

1987-06-05

1988-01-26

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514822, 514929, A61K 31495

Patent

active

047217138

ABSTRACT:
A method for inhibiting blood platelet aggregation in humans, and promoting vasodilation in humans, by administering to a human in need of the same an effective amount of 2-hydroxy-3-isopropyl-5,6-dimethylpyrazine or a hydrate or a pharmaceutically acceptable non-toxic salt thereof. Administration can be orally in an amount of about 0.02-12 mg/kg body weight per day, or parenterally in an amount of about 0.01-6 mg/kg of body weight per day.

REFERENCES:
patent: 3720768 (1973-03-01), Jones et al.
patent: 4599413 (1986-07-01), Kikumoto et al.
Jones; J. Am. Chem. Soc. 71: pp. 78-81 (1949).

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