Drug – bio-affecting and body treating compositions – Dentifrices – Oxygen or chlorine releasing compound containing
Patent
1996-11-26
1998-09-22
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Oxygen or chlorine releasing compound containing
424 49, 424 52, 424 57, A61K 716, A61K 718, A61K 720
Patent
active
058110801
ABSTRACT:
The method of manufacturing comprises the steps of: (a) preparing a mixture of a favor system, one or more humectants, and one or more aqueous carrier materials; (b) adding tetrasodium pyrophosphate and calcium peroxide, all at once or in portions, under conditions wherein less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; and wherein further any remaining aqueous carrier materials not added to the mixture during step (a) are added in whole or in part in step (b) or thereafter, either by themselves or with any remaining amount of the tetrasodium pyrophosphate or calcium peroxide, under conditions such that less than about 20% of the total pyrophosphate and calcium peroxide are dissolved in the mixture; (c) heating the mixture to a temperature range of from about 38.degree. C. (100.degree. F.) to about 71.degree. C. (160.degree. F.) and preferably to a temperature range of from about 52.degree. C. (125.degree. F.) to about 57.degree. C. (135.degree. F.), and (d) homogenizing the mixture in the temperature range for about 15 minutes to about 60 minutes. The tetrasodium pyrophosphate salt and peroxide are two of the last components to be added to the mixture, preferably after all or much of the other sodium-containing salts present in the composition have been added to the process mixture. By these methods, the dissolved tetrasodium pyrophosphate salt is less likely to recrystalize in the form of glass-like crystal particles of tetrasodium pyrophosphate decahydrate.
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Burgess Steven Carl
Sanker Lowell Alan
Upson James Grigg
Hentz Mary Catherine
Mohl Douglas C.
Rose Shep K.
Stone Angela Marie
The Procter & Gamble & Company
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