Process for inactivating the biological activity of DNA

Details Process for inactivating the biological activity of DNA Process for inactivating the biological activity of DNA

1992-09-08

1995-05-23

Wyse, Thomas

Liquid purification or separation

Processes

Treatment by living organism

210764, 210766, 422 28, C02F 150, A61L 204, C12N 108

Patent

active

054178622

ABSTRACT:
A process for inactivating the biological activity of DNA, especially recombinant DNA, is disclosed. The process includes the step of heating the DNA at 60.degree. to 100.degree. C. in the presence of an acid other than percarboxylic acid at a concentration of at least 0.2 mM and a pH value of maximum 4, preferably 3.

REFERENCES:
patent: 3227626 (1966-01-01), Baumgarten et al.
patent: 5120452 (1992-06-01), Ness et al.
Copy of European Search Report for corresponding European Application No. 91105898.0.

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