Process for inactivating hepatitis B virus

Details Process for inactivating hepatitis B virus Process for inactivating hepatitis B virus

1984-02-21

1986-05-27

Rosen, Sam

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

435236, A61K 3516

Patent

active

045915059

ABSTRACT:
A mammalian blood plasma or plasma derivative substantially free of active hepatitis B or non-A, non-B viruses is disclosed, the plasma being characterized by the presence of factor VIII, the percent by weight of denatured factor VIII to the sum of undenatured factor VIII and denatured factor VIII being less than 50%. The plasma is sterilized by contact with a detergent, alcohol or ether, and mixtures thereof and preferably a mixture of detergent and ether, usually followed by removal of the viral sterilizing agent.

REFERENCES:
patent: 4105650 (1978-08-01), Shanbrom

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