Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2005-12-27
2005-12-27
Spector, Lorraine (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C435S040000, C435S404000, C530S350000
Reexamination Certificate
active
06979532
ABSTRACT:
The present invention provides a process for identifying substances that modulate the activity of hyperpolarization-activated cation channels, and the use of this process.
REFERENCES:
patent: 6420183 (2002-07-01), Krahn et al.
patent: WO 99/11784 (1999-03-01), None
patent: WO 99/32615 (1999-07-01), None
patent: WO 99/42574 (1999-08-01), None
patent: WO 00/63349 (2000-10-01), None
patent: WO 00/73431 (2000-12-01), None
Hodder, et al, 2004, J. Biomol. Screening, 9(5): 417-426.
Vaccari, T. et al., “The Human Gene Coding for HCN2, a Pacemaker Channel of the Heart”, Biochim. et Biophys. Acta 1446(3):419-425, 1999.
Biel, M. et al., “Hyperpolarization-Activated Cation Channels: A Multi-Gene Family”,Rev. Physiol. Biochem. Pharmacol.136:165-181, 1999.
Hamill, O.P. et al., “Improved Patch-Clamp Techniques for High-Resolution Current Recording from Cells and Cell-Free Membrane Patches”,Pflügers Arch.391:85-100, 1981.
Ludwig, A. et al., “Two Pacemaker Channels from Human Heart with Profoundly Different Activation Kinetics”,EMBO J.18(9):2323-2329, 1999.
Langheinrich, U. and Jürgen Daut, “Hyperpolarization of isolated capillaries from guinea-pig heart induced by K+ channel openers and glucose deprivation”,Journal of Physiolog, 502.2:397-408, 1997.
Brüggemann Andrea
Gögelein Heinz
Heitsch Holger
Jansen Hans-Willi
Aventis Pharma Deutschland GmbH
Spector Lorraine
Wegert Sandra
LandOfFree
Process for identifying substances which modulate the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for identifying substances which modulate the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for identifying substances which modulate the... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3520418