Process for identifying FISH signals

Details Process for identifying FISH signals Process for identifying FISH signals

2007-03-13

2010-02-09

Johns, Andrew W (Department: 2624)

Image analysis

Applications

Biomedical applications

C382S255000, C382S284000

Reexamination Certificate

active

07660454

ABSTRACT:
The invention herein includes a method for combining immuno staining and FISH using covalently bound small molecule tags. Among embodiments included are methods of tagging immuno and FISH probes for treatment of biologic material. Embodiments comprise directing the fluorescently labeled immuno probe(s) to non-chromosomic portions of a biologic sample and directing labeled FISH probe(s) to chromosomic portions of the biologic sample for further identification of subcellular components. Embodiments also comprise the automatic connection of information regarding the sample to image analysis, to subcellular component identification and enumeration in order to affect biomedical decisions.

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