Process for hydrolysis of peptide or protein

Details Process for hydrolysis of peptide or protein Process for hydrolysis of peptide or protein

1985-12-24

1991-09-17

Schain, Howard E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

530407, C07K 310, C07K 112

Patent

active

050496573

ABSTRACT:
Peptide or protein are immobilized on a solid surface and exposed to acid mixture for hydrolysis. The acid mixture comprises mainly hydrocloride and trifruoracetic acid. The temperature of it is in the range of 100.degree. to 180.degree. C. The time period of exposing is in the range of 5 to 120 min.

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Proc. Japan Acad. 58, Ser. B (1982), 1-4, Tsugita et al.
Eur. J. Biochem. 124 (1982), 585-588, Tsugita et al.
Z. Physiol. Chem. 365 (1984), 343-345, Tsugita et al.

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