Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2007-08-14
2007-08-14
Davis, Brian (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C564S489000
Reexamination Certificate
active
10513321
ABSTRACT:
A process is provided for the hydrogenation or asymmetric hydrogenation of dialkyl, alkylalkenyl and dialkenyl imines of formula (II) to provide amines of formula (III), wherein, (i) R1and R2are optionally substituted cyclic, linear or branched alkyl or alkenyl; R3is a hydrogen atom, a hydroxy radical, optionally substituted C1to C8cyclic, linear or branched alkyl or alkenyl, optionally substituted aryl; or (ii) R1is alkyl or alkenyl, R2is alkyl or alkenyl and the two are linked together or with R3to form one or more rings; using a catalytic system comprising a base and a ruthenium complex containing (1) a diamine and (2) a diphosphine ligand or monodentate phosphine ligands in hydrogenation and asymmetric hydrogenation processes
REFERENCES:
patent: WO02/08169 (2002-01-01), None
Abdur-Rashid et al., Organometallics (2001), 20, p. 1047-1049.
Abdur-Rashid, K. et al., “RuHCl(diphosphine)(diamine): Catalyst Precursors for the Steroselective Hydrogenation of Ketones and Imines”, Organometallics, 2001, pp. 1047-1049, vol. 20.
Cobley, C. J. et al., “Enantioselective Hydrogenation of Imines using a Diverse Library of Ruthenium Dichloride (diphosphine) (diamine) Precatalysts”, Advanced Synthesis and Catalysis, 2003, pp. 195-201, vol. 345.
Henschke, J. P. et al., “Synthesis and Application of HexaPHEMP, a Novel Biaryl DiPhosphine Ligand”, Advanced Synthesis and Catalysis, 2003, pp. 300-307, vol. 345.
Cobley, C. J. et al., “The synthesis of S 18986, a chiral AMPA receptor modulator, via catalytic asymmetric hydrogenation”, Tetrahedron: Asymmetry, 2003, pp. 3431-3433, vol. 14.
Abdur-Rashid Kamaluddin
Morris Robert H.
Bereskin & Parr
Davis Brian
Folkins Patricia
LandOfFree
Process for hydrogenating unactivated imines using ruthenium... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for hydrogenating unactivated imines using ruthenium..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for hydrogenating unactivated imines using ruthenium... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3876620