Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1992-07-14
1993-11-23
Russel, Jeffrey E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530416, 530423, 530427, C07K 302, C07K 312, C07K 322, C07K 1506
Patent
active
052645550
ABSTRACT:
Methods are disclosed for separating hemoglobin from erythrocytes by contacting erythrocytes with a hypotonic buffer solution at a rate sufficient to render the release of hemoglobin from said erythrocytes without significant lysis. The hemoglobin is then separated from the erythrocytes. Methods are also disclosed for purifying hemoglobin solutions of DNA, endotoxins and phospholipids by contacting the hemoglobin solutions with an anion exchange medium.
REFERENCES:
patent: 4001200 (1977-01-01), Bonsen et al.
patent: 4001401 (1977-01-01), Bonsen et al.
patent: 4053590 (1977-10-01), Bosen et al.
patent: 4336248 (1982-06-01), Bonhard et al.
patent: 4412989 (1983-11-01), Iwashita et al.
patent: 4529719 (1985-07-01), Tye
patent: 4584130 (1986-04-01), Bucci et al.
patent: 4670417 (1987-06-01), Iwasaki et al.
patent: 4764279 (1988-08-01), Tayot et al.
patent: 4777244 (1988-11-01), Bonhard et al.
patent: 4900780 (1990-02-01), Cerny
patent: 5084558 (1992-01-01), Rausch et al.
patent: 5115100 (1992-05-01), Wu et al.
Rabiner et al., J. Exp. Med., 126, 1127 (1967).
DeVenuto et al., J. Lab. Clin. Med., 89, 509 (1977).
Bolin et al., "Advances In Blood Substitute Research", Prog. Clin. Biol. Res., 122, 117 (1983).
Litwin et al., An. Surg., 157(4), 485 (1963).
White et al., J. Lab. Clin. Med., 108(2), 121 (1986).
Simoni et al., Anal. Chim. Acta., 249, 169 (1991).
Hedlund et al., "Advances In Blood Substitute Research", Prog. Clin. Biol. Res., 122, 71 (1983).
Cho Myung-Ok P.
Czuba Barbara
Lee Chyi
Nho Kwang
Shankar Hariharan
Enzon Inc.
Russel Jeffrey E.
LandOfFree
Process for hemoglobin extraction and purification does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for hemoglobin extraction and purification, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for hemoglobin extraction and purification will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1850135