Process for heat treating thrombin

Details Process for heat treating thrombin Process for heat treating thrombin

1988-03-25

1990-05-08

Rosenberg, Peter D.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

435184, 435188, C12N 900

Patent

active

049238159

ABSTRACT:
An aqueous solution containing thrombin is heated in the presence of at least one stabilizer selected from various sugars to thereby inactivate viruses possibly contaminating said thrombin. According to this process, the inactivation of the contaminating viruses can be achieved while stably maintaining the thrombin. The stabilizing effect of this process can be further enhanced by using an amino acid as a stabilizer in combination with the sugar.

REFERENCES:
patent: 1599930 (1926-09-01), Takamine
patent: 1855592 (1932-04-01), Wallerstein
patent: 2495298 (1950-01-01), Szent-Gyorgyi
patent: 2567747 (1951-07-01), Wallerstein
patent: 3944470 (1976-03-01), Diehl
patent: 3950513 (1976-04-01), Jensen
patent: 4080262 (1978-03-01), Beancamp
patent: 4297344 (1981-10-01), Schwinn
patent: 4440679 (1984-04-01), Fernandes
patent: 4585754 (1986-04-01), Meisner
patent: 4623717 (1986-11-01), Fernandes
R. Murray, "Viral Hepatitis", New York Academy of Medicine, vol. 31, No. 5, pp. 341-358 (May, 1955).

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