Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1988-04-21
1992-05-26
Wax, Robert A.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530380, 435236, C07K 300
Patent
active
051169509
ABSTRACT:
An aqueous solution containing fibrinogen is heated in the presence of at least a sugar, an amino acid and a magnesium salt to thereby inactivate virus(es) possibly contaminating said fibrinogen. According to this process, the inactivation of the contaminating viruses can be achieved while maintaining the activity of the fibrinogen. Thus a highly safe fibrinogen preparation of excellent qualities can be prepared on an industrial scale.
REFERENCES:
patent: 4623717 (1986-11-01), Fernandes et al.
(Abstract, Dialog File 225, accession No. 8925134) Chandra et al., U.S. Pat. No. 4,876,241.
(Abstract, Dialog File 351, Accession No. 86-267871/41) Green Cross Corp., JP 61194035.
Murray, Bulletia of the New York Academy of Medicine, vol. 31, No. 5, pp. 341-358 (1955).
Iga Yoshiro
Miyano Kenmi
Nishimaki Hideo
Tanaka Kenji
Furman Keith C.
Green Cross Corporation
Wax Robert A.
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