Process for fermentatively producing vitamin B.sub.12

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Process involving micro-organisms of different genera in the...

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435 86, 435830, 435822, C12D 506

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042107202

ABSTRACT:
A process for fermentatively producing vitamin B.sub.12, which comprises cultivating a vitamin B.sub.12 -producing microorganism belonging to at least one of the genus Arthrobacter and the genus Propionibacterium in the presence of a pre-cultivation product of a vitamin B.sub.12 -producing microorganism belonging to at least the other genus, and separating vitamin B.sub.12 from the culture broth.

REFERENCES:
patent: 2785068 (1957-03-01), Hanson et al.
patent: 3085049 (1963-04-01), Rudy et al.
patent: 4119492 (1978-10-01), Kojima
Perlman, Advances in Applied Microbiology vol. 1, pp. 87-122, (1959).

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