Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...
Reexamination Certificate
2007-02-06
2007-02-06
Carr, Deborah D. (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Fatty compounds having an acid moiety which contains the...
C554S013000, C554S014000, C554S019000, C560S070000
Reexamination Certificate
active
10497077
ABSTRACT:
A process for extracting and isolating carotenoid esters or carotenoids in high purity from plants without the use of harmful organic solvents. Zeaxanthin esters were isolated and purified from the berries of Lycium Chinese Mill (LCM berries). The esters isolated according to the invention contain substantially no isomerized double bonds. The purified carotenoid esters or carotenoids isolated by this process are free from impurities and serve as a safe source of nutritional supplement for human consumption as well as providing a suitable and effective color additive for human foods.
REFERENCES:
patent: 4048203 (1977-09-01), Philip
patent: 5382714 (1995-01-01), Khachik
patent: 5523494 (1996-06-01), Torres-Cardona et al.
patent: 5648564 (1997-07-01), Ausich et al.
patent: 5780693 (1998-07-01), Bernhard et al.
patent: 5876782 (1999-03-01), Sas et al.
patent: 5902890 (1999-05-01), Nitsche et al.
patent: 5973211 (1999-10-01), Rodriguez
patent: 5998678 (1999-12-01), Sanroma Virgili et al.
patent: 6191293 (2001-02-01), Levy
patent: 6262284 (2001-07-01), Khachik
patent: 2003/0158455 (2003-08-01), Khachik
patent: 0 242 148 (1993-01-01), None
patent: 0 349 138 (1994-08-01), None
patent: 1 515 238 (1978-06-01), None
patent: 2 160 874 (1986-01-01), None
patent: 2 218 989 (1989-11-01), None
patent: 61-109764 (1986-05-01), None
patent: 07-304978 (1995-11-01), None
patent: WO 98/03480 (1998-01-01), None
patent: WO 99/20587 (1999-04-01), None
patent: WO 02/04415 (2002-01-01), None
patent: WO 03/048284 (2003-06-01), None
Auweter, H., et al., “Supramolecular Structure of Precipitated Nanosize β-Carotene Particles,”Angew. Chem. Int. Ed. 38:2188-2191, Wiley-VCH Verlag GmbH (1999).
Bone, R.A., et al., “Preliminary Identification of the Human Macular Pigment,”Vision Res. 25:1531-1535, Pergamon Press Ltd. (1985).
Bone, R.A., et al., “Stereochemistry of the Human Macular Carotenoids,”Invest. Ophthalmol. Vis. Sci. 34:2033-2040, Lippincott-Raven Publishers (1993).
Khachik, F., et al., “Identification of Lutein and Zeaxanthin Oxidation Products in Human and Monkey Retinas,”Invest. Ophthalmol. Vis. Sci. 38:1802-1811, Lippincott-Raven Publishers (1997).
Khachik, F., et al., “Identification, Quantification, and Relative Concentrations of Carotenoids and Their Metabolites in Human Milk and Serum,”Anal. Chem. 69:1873-1881, American Chemical Society (1997).
Khachik, F., et al., “Lutein, Lycopene, and Their Oxidative Metabolites in Chemoprevention of Cancer,”J. Cellular Biochem., Suppl.22:236-246, Wiley-Liss, Inc. (1995).
Khachik, F., et al., “Separation and Identification of Carotenoids and Their Oxidation Products in the Extracts of Human Plasma,”Anal. Chem. 64:2111-2122, American Chemical Society (1992).
Khachik, F., et al., “Separation, Identification, and Quantification of Carotenoids in Fruits, Vegetables, and Human Plasma by High Performance Liquid Chromatography,”Pure&Appl. Chem. 63:71-80, IUPAC (1991).
Khachik, F. and Beecher, G.R., “Separation of Carotenol Fatty Acid Esters by High-Performance Liquid Chromatography,”J. of Chromatography, 449:119-133, Elsevier Science Publishers B.V. (1988).
Lenfant, C. and Thyrion, F.C., “Extraction of carotenoids from palm oil II. Isolation methods,”Oléagineux Corps gras Lipides 3:294-307, John Libbey Eurotext (1996).
Murakoshi, M., et al., “Potent Preventive Action of α-Carotene against Carcinogenesis: Spontaneous Liver Carcinogenesis and Promoting Stage of Lung and Skin Carcinogenesis in Mice Are Suppressed More Effectively by α-Carotene Than by β-Carotene,”Cancer Res. 52:6583-6587, American Association for Cancer Research (1992).
Seddon, J.M., et al., “Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration,”J. Am. Med. Assoc. 272:1413-1420, American Medical Association (1994).
The Chemist's Companion: A Handbook of Practical Data, Techniques, and References,Gordon, A.J. and Ford, R.A., eds., John Wiley & Sons, Inc., New York, NY, pp. 451-452 (1972).
Tyczkowski, J.K. and Hamilton, P.B., “Research Note: Preparation of Purified Lutein and Its Diesters from Extracts of Marigold (Tagetes erecta),”Poultry Sci. 70:651-654, Poultry Science Association, Inc. (1991).
Patent Abstracts of Japan, Publication No. 61-109764, English Language Abstract for JP Patent Application No. 59-229023 (Document AN1).
Patent Abstracts of Japan, Publication No. 07-304978, English Language Abstract for JP Patent Application No. 06-098955 (Document AM2).
International Search Report for International Application No. PCT/US02/01108, US Commissioner of Patents and Trademarks, Washington, DC, mailed on Jul. 11, 2002.
Carr Deborah D.
Sterne Kessler Goldstein & Fox P.L.L.C.
University of Maryland College Park
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