Process for extracting type I collagen form an avian source, and

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.

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530420, 530427, 530840, A23J 110, C07K 302, C07K 1506

Patent

active

051380307

ABSTRACT:
A process for extracting type I collagen from an avian source such as poultry feet that incorporates a fibrillar mass of connective tissue as well as bony tissue to yield a collagen product having useful medical and biotechnology applications. In this process, after being cleaned and decontaminated, the poultry feet are comminuted and then enzyme-treated to enhance the yield. The enzyme-treated comminuted material which is rich in collagen is dispersed in an organic acid to cause the fibrillar mass to undergo controlled swelling, after which the mass is separated from the bony tissue and purified to remove non-collangenous material. The purified mass is dried to provide the desired Type I collagen product which may be ground into a powder or formed into a collagen matrix or sponge, depending on the end use therefor.

REFERENCES:
patent: 3014024 (1961-12-01), Lieberman et al.
patent: 4216204 (1980-08-01), Robertson
patent: 4260228 (1981-04-01), Miyata
patent: 4427583 (1984-01-01), England et al.
patent: 4841962 (1989-06-01), Berg et al.

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