Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2004-06-08
2008-05-13
Lankford, Jr., Leon B. (Department: 1651)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
C435S004000, C435S029000, C435S366000, C435S384000, C424S093700
Reexamination Certificate
active
07371575
ABSTRACT:
The present invention concerns methods for the ex vivo formation of mammalian bone and subsequent uses of the bone. A critical and distinguishing feature of the present invention are defined tissue culture conditions and factors resulting in the formation of bone cell spheroids. The invention also provides for methods of implanting into subjects the ex vivo formed bone. Also described are methods for genetically altering the bone cell spheroids to affect bone formation, identification of candidate modulators of bone formation, and identification of genes involved in bone formation.
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Kale Sujata
Long Michael W.
Ford Allison M.
Fulbright & Jaworski LLP
Lankford , Jr. Leon B.
The Regents of The University of Michigan
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