Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1982-08-19
1983-09-13
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435121, 435886, C12P 1712, C12P 1710, C12R 1465
Patent
active
044042825
ABSTRACT:
Angiotensin I converting enzyme inhibitor A-58365 factor B is provided in greater abundance than coproduced Factor A by culturing Streptomyces chromofuscus NRRL 15098 under submerged aerobic fermentation conditions in an aqueous nutrient culture medium supplement with the amino acids proline and lysine.
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patent: 4316905 (1982-02-01), Krapcho
patent: 4316906 (1982-02-01), Ondetti et al.
Cushman, D. W. et al., Federation Proceedings, vol. 38, No. 13, Dec. 1979.
Derwent abstract 25836D/15 of EP25-941.
A. A. Patchett et al., Nature, 288:280-283, 1980.
Eli Lilly and Company
Scanlon William B.
Shapiro Lionel M.
Whale Arthur R.
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