Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-03-01
1993-12-14
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 772, 435 79, 435 792, 435 21, 435968, 436518, C12Q 168, G01N 33535
Patent
active
052701646
ABSTRACT:
A process is disclosed for the enhancement of the chemiluminescence of enzyme-triggered 1,2-dioxetanes detectable within a sample. The process comprises first providing a solid support having sample disposed thereon and suitably treated with a solution including enzyme-triggered 1,2-dioxetanes. The solid support is next dried and optionally heated either simultaneously with drying or thereafter. The steps of drying and/or heating are conducted either prior to or simultaneously with detection.
REFERENCES:
patent: 4705847 (1987-11-01), Hummelen et al.
patent: 4857652 (1989-08-01), Schaap
patent: 4948975 (1990-08-01), Erwin et al.
patent: 4952707 (1990-08-01), Edwards et al.
patent: 4956477 (1990-09-01), Bronstein et al.
patent: 4959182 (1990-09-01), Schaap
patent: 5089423 (1993-02-01), Diamandis et al.
Schaop et al Tetrahedron Letters 78 #11 pp. 1159-1162 (1987).
Wood J. Clin. Chem. Clin. Biochem. 38 pp. 481-483 (1990).
Pollard-Knight et al. Anal. Biochem. 185 pp. 353-358 (1990).
Beck & Koster, Analytical Chemistry, vol. 62, No. 21, Nov. 1, 1990.
Bronstein et al., J. Biolumin, Chemilumin. 4, 99-111 (1989).
J. C. Hummelen et al., Methods in Enzymology, vol. 133, pp. 531-557 (1986).
Kiel, Bioelectromagnetics 4, 193-204 (1983).
Southern Light Protocol.
Photogene Nucleic Acid Detection System.
Willard, Merritt, Dean and Settle, Methods of Analysis, Sixth Edition, D. Van Nostrand & Co., 1981 pp. 111-113.
A. K. Campbell, Chemiluminescence: Principles and Applications in Biology and Medicine, Eliis Horwood Publishing Co., 1988, pp. 81-87.
Anderson Lynne E.
Kobos Robert K.
Polsky Shay E.
E. I. Du Pont de Nemours and Company
Green Lora Marie
Kepplinger Esther L.
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