Process for enantioselective synthesis of single enantiomers...

Details Process for enantioselective synthesis of single enantiomers... Process for enantioselective synthesis of single enantiomers...

2008-05-06

2008-05-06

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C560S011000

Reexamination Certificate

active

07368591

ABSTRACT:
The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent; and optionallyb) isolating the obtained sulphoxide of formula (I).wherein n, Y, R1, R1a, R2and R2aare as defined in claim1.

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