Process for enantioselective synthesis of single enantiomers...

Details Process for enantioselective synthesis of single enantiomers... Process for enantioselective synthesis of single enantiomers...

2008-01-08

2008-01-08

Shiao, Rei-tsang (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

Reexamination Certificate

active

07317126

ABSTRACT:
The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent; and optionallyb) isolating the obtained sulphoxide of formula (I);wherein n, Y, R1, R1a, R2and R2aare as defined herein.

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