Process for determining tumor-associated glycolinkage

Details Process for determining tumor-associated glycolinkage Process for determining tumor-associated glycolinkage

1982-01-29

1984-06-19

Padgett, Benjamin R.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

Utilizing isolate of tissue or organ as binding agent

436501, 436 63, 436 64, 436 94, 436808, 436813, 435 4, 435188, 260112R, 422 61, G01N 3356, G01N 3358, G01N 3360, G01N 3368

Patent

active

044553803

ABSTRACT:
A process for determining the level of TAG in a sample of body fluid which comprises reacting the TAG in a sample of body fluid with an AG-binding lectin or L-fucose-binding lectin to form a TAG-lectin complex and measuring the amount of the TAG-lectin complex or an unreacted lectin is disclosed. The process shows low cross-reactivity with hepatic diseases and is useful for diagnosis of cancers.

REFERENCES:
patent: 4146603 (1979-03-01), Davidson et al.
patent: 4289747 (1981-09-01), Chu
patent: 4334017 (1982-06-01), Plotkin et al.
patent: 4389392 (1983-06-01), Adachi

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