Process for determining the binding capacity of thyroxin-binding

Details Process for determining the binding capacity of thyroxin-binding Process for determining the binding capacity of thyroxin-binding

1986-12-23

1988-11-22

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436500, 436512, 436518, 436532, 436548, 436817, G01N 3353, G01N 33543, G01N 33549

Patent

active

047865911

ABSTRACT:
The present invention provides a process for determining the binding capacity of thyroxin-binding globulin (TBG) according to the principle of heterogeneous enzyme immunoassay, wherein the serum sample to be investigated is incubated with enzyme-labelled T.sub.4 or T.sub.3 and immobilized antibody against TBG or T.sub.4, the phase are separated and the labelling enzyme is measured in one of the phases.

REFERENCES:
patent: Re32098 (1972-06-01), Chopra
patent: 4366143 (1980-09-01), Midgley et al.
patent: 4410633 (1980-09-01), Hertl et al.
patent: 4467030 (1984-08-01), Kleinhammer et al.
patent: 4476228 (1982-11-01), Huchzermeier et al.
patent: 4481298 (1984-11-01), Cone et al.
patent: 4636478 (1987-01-01), Siebert et al.
The Merck Manual, 14th edition (1982), pp. 997-1000.
Diagnostic Tests Handbook (1986), p. 143, publisher Keith Lassner, editor Regina Daley Ford.
Alberts et al., Molecular Biology of the Cell, published by Garland Publishing Inc., 1983, pp. 958-959.
Alberts et al., Molecular Biology of the Cell, published by Garland Publishing Inc., 1983, p. 966.

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