Chemistry: analytical and immunological testing – Oxygen containing – Hydroxyl containing
Patent
1994-08-25
1995-11-28
Housel, James C.
Chemistry: analytical and immunological testing
Oxygen containing
Hydroxyl containing
436127, 436132, 436169, 436172, 436178, 422 84, 422 85, 422 86, 422 87, G01N 3314
Patent
active
054707552
ABSTRACT:
Hemiacetals are disclosed which correspond to the following formula II ##STR1## in which R' is an aliphatic or cycloaliphatic residue,
Ar is an unsubstituted or substituted monocyclic or polycyclic aromatic or heteroaromatic residue and
X.sup.1, X.sup.2 and X.sup.3 are selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, fluoro, chloro, bromo and nitro, wherein however at least one of said substituents has to be selected from the stated halo atoms or nitro. The hemiacetals are formed reversibly from an alcohol and a corresponding keto compound and the hemiacetals of formula II differ from the corresponding keto compounds as to their light absorption in the ultraviolet, visible or infrared range, or a fluorescence or luminescence is created or quenched when the keto compound is converted into the hemiacetal of formula II. Said reaction can be performed in sensors which are used for the optical determination of alcohols.
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Housel James C.
Soderquist Arlen
Willi Moller AG
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