Process for detecting the presence of malignant and pre-malignan

Details Process for detecting the presence of malignant and pre-malignan Process for detecting the presence of malignant and pre-malignan

1980-06-05

1982-03-02

Hruskoci, Peter A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

424 8, 424 12, 435 4, 435 15, G01N 3354

Patent

active

043178774

ABSTRACT:
Malignant and pre-malignant cells in humans are detected by contacting an antibody to oncofoetal deoxythymidine kinase with human cells and detecting the presence of cells containing oncofoetal deoxythymidine kinase antigen bound to the antibody.

REFERENCES:
patent: 3663684 (1972-05-01), Freedman et al.
patent: 3974269 (1976-08-01), Maley
Salser, Cancer Research, 36, 1976, pp. 3495-3498.
Taylor, J. Biol. Chem., 247, 1972, 1930-1935.
Salser et al., Nature 260, 1976, pp. 261-263.
Chemical Abstracts 90:127518p "Specific Immunoserums," Matsuda et al. 1978.
Ibsen, Biochim. Biophys. Acta, 560, 1979, pp. 243-280.
Rees, Methods of Cancer Research 18, 1979 pp. 99-133.

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