Process for detecting PrP using a macrocyclic adjuvant ligand

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007920, C435S023000, C435S961000, C436S524000, C436S532000, C436S823000, C530S403000, C530S807000

Reexamination Certificate

active

11148945

ABSTRACT:
A process for detecting the forms of the prion pathogens responsible for subacute, transmissible, spongiform encephalopathies, including a macrocyclic adjuvant ligand (AML), free or bound to a support, that is added to a biological sample capable of containing PrPsc, the resulting suspension then being reacted with an anti-PrPscantibody, and the presence of PrP is then detected.

REFERENCES:
patent: 5571911 (1996-11-01), Still et al.
patent: 5891641 (1999-04-01), Prusiner et al.
patent: WO 97/37995 (1997-10-01), None
patent: WO 01/23425 (2001-04-01), None
patent: WO 01/77687 (2001-10-01), None
patent: WO 02/086511 (2002-10-01), None

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