Process for cultivation of hemolytic Streptococcus pyogenes

Details Process for cultivation of hemolytic Streptococcus pyogenes Process for cultivation of hemolytic Streptococcus pyogenes

1980-04-16

1981-12-15

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using bacteria

435 68, 435244, 435253, 435885, C12N 120, C12N 138, C12R 146

Patent

active

043060242

ABSTRACT:
A process for cultivation of Streptococcus pyogenes comprising cultivating Streptococcus pyogenes in a culture medium for multiplication of bacterial cells having an anti-tumor activity, characterized by (A) using the culture medium containing fermentable carbon sources and (B) maintaining pH of the culture medium at 5.6 or more during the course of cultivation.

REFERENCES:
patent: 3477914 (1969-11-01), Okamoto et al.
patent: 3627644 (1971-12-01), Okamoto et al.
Okamoto et al., Gann, 55, 225-232 (1964).
Okamoto et al., Japan J. Exp. Med., 34(3), 109-118 (1964).
Ohtsuki, Annual Reports of the Research Institute for Cancer, Kanazawa University, vol. 1, 141-153 (1967).

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