Process for cultivating adhesive cells in a packed bed of solid

Details Process for cultivating adhesive cells in a packed bed of solid Process for cultivating adhesive cells in a packed bed of solid

1990-11-26

1993-11-09

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

43524023, 435176, 435311, C12N 502, C12N 500, C12N 1114, C12M 112

Patent

active

052602117

ABSTRACT:
A process and system for cultivating adhesive cells in a packed bed of solid cell matrix is disclosed. Adhesive cells are adhered to a solid cell matrix, preferably ceramic particles, and packed in a cell culture tank to form the packed bed. The culture medium is circulated through the packed bed in a direction. The circulating of the culture medium is then stopped and the direction of the medium being circulated is reversed. This periodic switching of the direction of the culture medium reduces channelling of the culture medium. The bottom or head of the culture tank can also contain a separator to trap any bubble existing in the culture medium or to trap any quantity of cell matrix possibly running out from the culture tank.

REFERENCES:
patent: 4144126 (1979-03-01), Burbidge
patent: 4542101 (1985-09-01), Nees
patent: 4649117 (1987-03-01), Familletti
patent: 4833083 (1989-05-01), Saxena
patent: 4889812 (1989-12-01), Guinn et al.
patent: 4894342 (1990-01-01), Guinn et al.

Affiliated with

Also associated with

Rating

Process for cultivating adhesive cells in a packed bed of solid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for cultivating adhesive cells in a packed bed of solid , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for cultivating adhesive cells in a packed bed of solid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1142314