Process for crystalline cyclic lipopeptides

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides

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530344, C07K 114, C07K 754

Patent

active

053367561

ABSTRACT:
A process for obtaining a compound of the formula ##STR1## in crystalline form by solubilizing the compound in warm aqueous n-propanol and then allowing the solution to stand at ambient temperature until crystal formation is substantially complete is described. The crystalline compound obtained thereby is also described.

REFERENCES:
patent: 5198421 (1993-03-01), Chen et al.
patent: 5202309 (1993-04-01), Schwartz et al.
Weissberger, Technique of Org. Chem., Part 1, Separation & Purif. (Intersci. Pub. Inc. New York), 1956, pp. 548-561.

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