Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-06-30
1999-08-03
Richter, Johann
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548950, 548964, 548967, 548579, 546208, 546246, 544162, C07D20712, C07D20504, C07D20308, C07D40106
Patent
active
059327456
ABSTRACT:
This invention concerns the use of a hydroxylic solvent in the preparation of enaminones from the corresponding amine N-oxides or propargylic amines via the general process outlined below: ##STR1##
REFERENCES:
patent: 4937235 (1990-06-01), Trybulski et al.
patent: 5059709 (1991-10-01), Dusza et al.
patent: 5550257 (1996-08-01), Trybulski et al.
Hallstrom et al., Decomposition of Prop-2-ynylic N Oxides . . . , Tetrahedron Letters, vol. 21, pp. 667-670, Dec. 1980.
Greenhill, J.V. Chem. Soc. Rev. 1977, 6, 277.
Mannich, C., et al., Chem Ber. 1933, 66, 418.
Sanogashira, et al. Tetrahedron Lett. 1975, 4467 Unroe, M.R., et al. Synthesis 1978, 981.
Unroe, M.R., et al. Synthesis 1978, 981.
Stille, J.K. Angew. Chem. Intl. Ed. Engl. 1986, 25, 508.
Scott, W.J. et al. Acc. Chem. Res. 1988, 21, 47.
Kalinin, V.N. Synthesis 1992, 413.
Ritter, K. Synthesis 1993, 735.
Albini, A. Synthesis 1993, 263.
Murray, R.W. Chem. Rev. 1989, 1187.
Torregrosa, J.L. et al. Tetrahedron 1982, 38, 2355.
McMullen, C.H. et al. J. Chem Soc. 1966, 1217.
Hales, N.J. et al. Tetrahedron 1995, 51, 7403.
Ligouri, A. et al. Tetrahedron 1988, 44, 1255.
Craig, J.C. et al. Tetrahedron Lett. 1979, 4025.
Hallstrom, G. et al. Tetrahedron Lett. 1980, 21, 667.
Khuthier, A-H. et al. J. Chem. Soc. Chem. Comm. 1979, 9.
Weizmann, J. Amer. Chem. Soc. 1949, 71, 4154.
Hirao, I. J. Chem. Soc. Japan 1953, 968.
Neale, R.S. et al. J. Org. Chem. 1964, 29, 3390.
Katritzky, A.R. et al. Synthesis 1989, 949.
Clarke, H.T. et al. Organic Synthesis, vol. I 1941, 514.
Kucklaender, U. "Enaminones as Synthons", in Chemistry of Enamines,
Craig et al., J. Org. Chem., vol. 35, No. 5., May 1970, pp. 1721-1722.
Dushin Russell G.
Trybulski Eugene J.
American Home Products Corporation
Eck Steven R.
Keating Dominic
Richter Johann
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