Process for converting neopinone to codeinone

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07D48900, C07D48902

Patent

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040545660

ABSTRACT:
A process for converting neopinone alkaloid to codeinone alkaloid which involves treating neopinone with a hydrohalic acid in a suitable solvent under anhydrous conditions. It also relates to the compound 8-halodihydrocodeinone hydrohalide.

REFERENCES:
Rapoport et al., J. Am. Chem. Soc. 89(8), pp. 1942-1947 (1967).

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