Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1992-07-13
1994-05-24
Griffin, Ronald W.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435170, 435262, 435280, 536117, 5361231, 424 88, 424 92, 210601, 210616, 210631, C12P 1904, C12P 104, C12R 121
Patent
active
053148118
ABSTRACT:
A process for converting lipid-containing bacterial capsular polysaccharide, such as lipo-polyribosyl ribitol phosphate, lipo-PRP, into lipid-free, endotoxin-free polysaccharide, such as polyribosyl ribitol phosphate, PRP, by solubilizing polysaccharide-containing powder derived from culture media of bacteria, such as Haemophilus influenzae type b, cleaving covalently bound fatty acids from the polysaccharide, and removing the lipids, and endotoxin.
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Lee Ann L.
Manger Walter E.
Rienstra Mark S.
Sitrin Robert D.
Bencen Gerard H.
Griffin Ronald W.
Matukaitis Paul D.
Merck & Co. , Inc.
Tribble Jack L.
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