Process for conditioning of water-soluble substances

Details Process for conditioning of water-soluble substances Process for conditioning of water-soluble substances

1995-06-07

1996-10-08

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424488, 424490, A61K 914

Patent

active

055629237

ABSTRACT:
A process for providing water-soluble micronized pharmaceutically acceptable inhalable substances, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation of the pharmaceutically acceptable substances. This process is carried out by the steps of reducing, if necessary, the residual water from the micronized substance by drying at an elevated temperature and/or vacuum; conditioning the dried, micronized pharmaceutically acceptable inhalable substances with a solvent; and eliminating residual solvent by storing under dry conditions as, e.g., in a vacuum or by purging with a dry, inert gas.

REFERENCES:
patent: 3978192 (1976-10-01), Wright
patent: 4405598 (1983-09-01), Brown
patent: 4476130 (1984-10-01), Wade

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