Process for coating active principles using a pH-sensitive polym

Drug – bio-affecting and body treating compositions – Digestive system regulator containing solid synthetic...

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424468, 424482, 514964, 523105, A61K 924

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active

052962199

ABSTRACT:
A process for coating at least one medicinal and/or foodstuff active principle useful for ruminants. At least one monomer is polymerized in an oil-in-water emulsion in the presence of a surfactant to synthesize a pH-sensitive-polymer composition, the composition being obtained in an oil-in-water emulsion. Without isolation of the pH-sensitive polymer, the oil-in-water emulsion is used to coat the active principle, preferably methionine or lysine or a derivative thereof. The pH-sensitive polymer is not dissolved in an organic solvent(s) in either the polymerization or coating steps. The pH-sensitive polymer is stable at pH 6 but at pH 2, the coated active principle is released.

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