Process for cleaving an imido side chain from penicillins and ce

Details Process for cleaving an imido side chain from penicillins and ce Process for cleaving an imido side chain from penicillins and ce

1973-06-18

1977-01-25

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260243C, 424271, 424246, C07D50120

Patent

active

040050742

ABSTRACT:
The amic acid group of a 7-(amic acid) cephalosporin or 6-(amic acid) penicillin is cleaved by dehydration to the corresponding novel 7-isoimidocephalosporin or 6-isoimido-penicillin, and cleavage of the 7-isoimidocephalosporin or 6-isoimidopenicillin to the corresponding 7-aminocephalosporin or 6-aminopenicillin or to a corresponding 7-acylamidocephalosporin or 6-acylamidopenicillin.

REFERENCES:
patent: 3487074 (1969-12-01), Sheehan
patent: 3843682 (1974-10-01), Kukolja et al.

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