Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1979-04-12
1980-10-28
Roberts, Elbert L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2603972, 2603974, C07J 900, C07J 500
Patent
active
042306256
ABSTRACT:
A multi-step synthesis of chenodeoxycholic acid from 3-keto-bisnorcholenol, a compound readily obtained from the abundant plant sterol .beta.-sitosterol, is described. A key step in the synthesis is the stereoselective microbial introduction of the 7-alpha hydroxy group into 3-keto-bisnorcholenol.
REFERENCES:
patent: 3655650 (1972-04-01), Furst et al.
patent: 3856780 (1974-12-01), Narwid et al.
Despreaux Carl
Narwid Thomas A.
Palleroni Norberto J.
Uskokovic Milan R.
Callwood James H.
Gould George M.
Hoffmann-La Roche Inc.
Roberts Elbert L.
Saxe Jon S.
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