Process for certain (2R-trans)hexahydroaroquinolizines

Details Process for certain (2R-trans)hexahydroaroquinolizines Process for certain (2R-trans)hexahydroaroquinolizines

1990-04-09

1991-11-12

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 50, 546 62, 546 64, C07D22118

Patent

active

050649647

ABSTRACT:
A unique process for preparing certain (2R-trans)hexahydroaroquinolizines, especially (2R-trans)-N-[2-(1,3,4,6,7,12b-hexahydro-2'-oxospiro[aro-[2,3-a]-quinolizi ne-2,4'-imidazolidin]-3'-yl) ethyl)-methanesulfonamide from (2R-trans)-N-[2-[(2-cyano-(1,3,4,6,7,12b-hexahydro-aro-[2,3-a]quinolizin-2 -yl)amino]ethyl]methanesulfonamide is described.

REFERENCES:
patent: 4831035 (1989-05-01), Baldwin et al.
patent: 4916233 (1990-04-01), Baldwin et al.

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