Process for cephem synthesis

Details Process for cephem synthesis Process for cephem synthesis

1975-10-21

1978-04-25

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 16, 544 22, 544 24, 544 25, 544 26, 544 27, 544 28, 544 29, 544 30, C07D50108

Patent

active

040864235

ABSTRACT:
Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##

REFERENCES:
patent: 3534029 (1970-10-01), Beyerman
patent: 3962224 (1976-06-01), Christensen et al.
patent: 3987040 (1976-10-01), Cheng et al.
Ratcliffe et al., Tetrahedron Letters, 1973, No. 46, pp. 4643-4646.

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