Process for cephem prodrug esters

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540221, 540226, C07D50104

Patent

active

049355082

ABSTRACT:
A process for the selective formation of oximino o-protected derivatives of lower alkyl 2-(2-aminothiazol-4-yl)-2-oximinoacetates, and their use in the acylation of 7-amino-cephalosporin compounds is disclosed.

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patent: 4714760 (1987-12-01), Brundidge et al.
R. Bucourt, et al., Tetrahedron Letters, vol. 34, pp. 2233-2243 Amino-2-Thiazolyl-4-Acetyles.

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