Process for benz[f]-2,5-oxazocines

Details Process for benz[f]-2,5-oxazocines Process for benz[f]-2,5-oxazocines

1975-03-07

1976-08-31

Milestone, Norma S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D26722

Patent

active

039780856

ABSTRACT:
An improved process is described for the preparation of 5-lower alkyl-1-phenyl-1,3,4,6-tetrahydro-5H-benz[f]-2,5-oxazocines in which 2-(N-hydroxyethyl=N=lower alkylaminomethyl)-benzhydrols are cyclized in the presence of aqueous hydrogen halide.

REFERENCES:
houben-Weyl, vol. 6/4 (1966), pp. 510-518.
Chem. Berichte, vol. 95, No. 5, (1962), pp. 1451, 1454, 1455, 1458, 1459.
Jour. Medicinal and Pharmaceutical Chemistry, vol. 3, No. 1 (1961).
Jour. Am. Chem. Soc., vol. 58 (1936), pp. 2338-2339.
Arzneim.-Forsch., vol. 22, No. 1 (1972), pp. 132-133.

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