Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1974-11-18
1976-04-06
Gotts, Lewis
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
424359, A61K 3700, A01N 900
Patent
active
039490734
ABSTRACT:
A method for augmenting hard or soft connective tissue, such as skin, tendon, cartilage, bone or interstitium, in a living mammal comprising implanting a proteolytic enzyme-solubilized, purified, native, in situ polymerizable collagen solution into the mammal at the augmentation site. The solution polymerizes at the site into a stable, non-reactive fibrous mass of tissue which is rapidly colonized by host cells and vascularized.
REFERENCES:
patent: 3469003 (1969-09-01), Hardy
Shoshan et al.: Chem. Abstr. 74: 30657q (1971).
Rouveix: Chem. Abstr. 73: 133993e (1970).
Bedacht: Chem. Abstr. 74: 109758q (1971).
Daniels John R.
Knapp Terry R.
Ciotti Thomas E.
Gotts Lewis
Suyat Reginald J.
The Board of Trustees of Leland Stanford Junior University
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