Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-one

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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546226, 546233, C07D47104

Patent

active

047911999

ABSTRACT:
This invention relates to a process for preparing useful antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones from 1-acyl-.alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl-2-piperid ineacetamides. This invention also relates to the 1-acyl-.alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl-2-piperid ineacetamides employed in this process.

REFERENCES:
patent: 4560754 (1985-12-01), Adelstein et al.
patent: 4585863 (1986-04-01), Deinhammer et al.
patent: 4680295 (1987-07-01), Fowler et al.

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