Process for alleviating proliferative skin diseases

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424203, 424240, 424273R, 424319, 424326, 424327, A61K 31275, A61K 3115

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active

042017882

ABSTRACT:
A process and pharmaceutical compositions for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans or domesticated animals, topically and/or parenterally, and/or systemically a composition comprising a pharmaceutical carrier and at least one diamino compound selected from the diamines of saturated and unsaturated aliphatic hydrocarbons having 3 to 6 carbon atoms and the diamines of saturated monocarboxylic acids having 4 to 6 carbon atoms and the alkyl esters thereof containing from 1 to 4 carbon atoms. These diamino compounds are usable alone or in combination with certain prostaglandin compounds, certain phosphodiesterase inhibitor compounds and certain cyclic adenosine monophosphate compounds.

REFERENCES:
patent: 4007268 (1977-02-01), Voorhees
patent: 4009282 (1977-02-01), Voorhees
patent: 4034087 (1977-07-01), Voorhees
Cancer Research, 34, 886-892, (1974).
Biochimica et Biophysica Acta, 473, (1978), 241-293.
Handbook of Non-Prescription Drugs, 5th ed., 332, (1977).
Physicians Desk Reference, 26th ed., pp. 809-811, (1972).

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