Process for aligning macromolecules by passage of a meniscus...

Details Process for aligning macromolecules by passage of a meniscus... Process for aligning macromolecules by passage of a meniscus...

2006-10-17

2006-10-17

Fredman, Jeffrey (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

Reexamination Certificate

active

07122647

ABSTRACT:
A product includes a surface on which a coupled complex is aligned, adherent, and stationary, obtained by a process that includes providing a support having a surface with a molecule with biological activity attached, contacting the surface with a sample containing a macromolecule to couple the macromolecule to the molecule on the surface, passing a meniscus over the coupled complex to align the coupled complex, and detecting the macromolecule in the coupled complex. The product is alternatively obtained by passing a meniscus over the molecule with biological activity prior to contacting the surface with a sample containing a macromolecule to couple the macromolecule to the molecule on the surface.

REFERENCES:
patent: 4278651 (1981-07-01), Hales
patent: 4539061 (1985-09-01), Sagiv
patent: 4562157 (1985-12-01), Lowe et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4698302 (1987-10-01), Whitehead et al.
patent: 4724207 (1988-02-01), Hou et al.
patent: 4921809 (1990-05-01), Schiff et al.
patent: 5019416 (1991-05-01), Honzawa
patent: 5098977 (1992-03-01), Frautschi et al.
patent: 5102798 (1992-04-01), Guiseppi-Elie
patent: 5178947 (1993-01-01), Charmot et al.
patent: 5215882 (1993-06-01), Bahl et al.
patent: 5232829 (1993-08-01), Longiaru et al.
patent: 5237016 (1993-08-01), Ghosh et al.
patent: 5240846 (1993-08-01), Collins et al.
patent: 5330891 (1994-07-01), Sutton
patent: 5372930 (1994-12-01), Colton et al.
patent: 5447841 (1995-09-01), Gray et al.
patent: 5610287 (1997-03-01), Nikiforov et al.
patent: 5624711 (1997-04-01), Sundberg et al.
patent: 5677126 (1997-10-01), Bensimon et al.
patent: 5840862 (1998-11-01), Bensimon et al.
patent: 5846724 (1998-12-01), Bensimon et al.
patent: 5851769 (1998-12-01), Gray et al.
patent: 6054327 (2000-04-01), Bensimon et al.
patent: 6130044 (2000-10-01), Bensimon et al.
patent: 6265153 (2001-07-01), Bensimon et al.
patent: 6294324 (2001-09-01), Bensimon et al.
patent: 6303296 (2001-10-01), Bensimon et al.
patent: 3717210 (1988-12-01), None
patent: 0 125 995 (1984-11-01), None
patent: 0 127 438 (1984-12-01), None
patent: 0 350 407 (1990-01-01), None
patent: 0 388 940 (1990-09-01), None
patent: 0 391 674 (1990-10-01), None
patent: 0 435 785 (1990-12-01), None
patent: 0 578 148 (1994-01-01), None
patent: WO93/22463 (1993-11-01), None
patent: WO97/06278 (1997-02-01), None
Houmelda et al., “Studies of the Interaction Between Titin and Myosin”, J. Cell. Biol. 131:1471-1481 (1995).
Nave et al., “Visualization of the Polarity of Isolated Titin Molecules: A Single Globular Head on a Long Thin Rod as the M Band Anchoring Domain”, J. Cell Biology, vol. 109:2177-2187 (1989).
Preliminary Search Report, Nov. 14, 1994, FR 94/07444.
Preliminary Search Report, Nov. 14, 1994, FR 94/01574.
Zimmerman et al., “DNA Stretching on Functionalized Gold Surfaces,”Nucleic Acids Res.22:3 (1994), pp. 492-497.
Schwartz et al., “Ordered Restriction Maps of S.CerevisiaeChromosomes Constructed by Optical Mapping,”Science262:5130 (Oct. 1993), pp. 110-114.
Parra et al., “High Resolution Visual Mapping of Stretched DNA by fluorescent Hybridization,”Nature Genetics,vol. 5 (Sep. 1993), pp. 17-21.
Lund et al., “Assessment of Methods for Covalent Binding of Nucleic Acids to Magnetic Beads, Dynabeads™, and the Characteristics of the Bound Nucleic Acids in Hybridization Reactions,”Nucleic Acids Res.16 (1988), pp. 10861-10880.
Bensimon et al., “Alignment and Sensitive Detection of DNA by a Moving Interface”,Science,vol. 265, pp. 2096-2098 (Sep. 1994).
Keller et al.,PNAS,vol. 86, pp. 5356-5360.
Beattie et al., “Hybridization of DNA Targets . . . ”,Molecular Biotechnology,vol. 4, pp. 213-225 (1995).
Netzer et al., “A New Approach to Construction . . . ”,J. Amer. Chem. Soc.,vol. 105, No. 3, pp. 674-676 (1983).
Tskhovreboa et al., “Direct Visualization of Extensibility in Isolated Titin Molecules”,J. Mol. Biology,vol. 265, pp. 100-106 (1997).

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