Process for 4"-epi-acetylamino-4"-deoxy-5-oximinoavermectin B.su

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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549264, C07H 1708, A01N 4304

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054202604

ABSTRACT:
An improved process for formation of a 5-oxime on avermectin derivatives comprises the treatment of the oxo-compound with hydroxylamine in aqueous isopropanol at pH 1.8-2.1.

REFERENCES:
patent: 4427663 (1984-01-01), Mrozik
patent: 5015630 (1991-05-01), Fisher et al.
patent: 5023241 (1991-06-01), Linn et al.
Ag. & Biol. Chem., vol. 55, No. 10, pp. 2615-2621 (1991), by Tsukamoto, et al.
C. R. Acad. Sc. Paris, t. 270 (12 Janvier 1970), pp. 240-242, by Frainnet, et al.

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