Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde

Details Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde

1988-11-17

1990-02-13

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

564305, C07B 4106, C07C12152

Patent

active

049008595

ABSTRACT:
4-Dimethylamino-3,5-dimethoxy-benzaldehyde, an intermediate for the preparation of the antibacterially active aditoprim (4-dimethylamino-3,5-dimethoxybenzoldehyde) a known antibacterially active compound, is obtained from 4-dimethylaminobenzonitrile by bromination or chlorination, replacement of the halogen by the methoxy group and reduction of the nitrile group.

REFERENCES:
patent: 3933887 (1976-01-01), Gengnagel
patent: 3971821 (1976-07-01), Baumann et al.
patent: 4273785 (1981-06-01), Shepherd
patent: 4440950 (1984-04-01), Drake
patent: 4515948 (1985-05-01), Kompis et al.

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